Connection issues with pods on Centos 8 nodes

So apparently the problem is cause centos8 uses nftables. Thus you have to update the calico-dameonset with the following environment variable

....
    Environment:
      FELIX_IPTABLESBACKEND:              NFT
....

Credits go to https://github.com/rancher/rke/issues/1788#issuecomment-565536201

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