Is Raspberry Pi, Microk8's and Istio Possible?

Working with my Pi cluster I want to move to using istio. I know core isn’t supposed, but is there any way to get it deployed? With or without addons

I don’t think istio services is supported on arm64 arch yet.
If you are interested on service meshes, i highly recommend linkerd.
It can run on arm64. If you are using 1.21, linkerd v2.9.4 is included in the addon.

More info on linkerd here